BRAE SCIENTIFIC
Fatigue
Fatigue in Men
Losing your edge? Feeling drained all the time can take a toll on every area of life. Fatigue is one of the most common symptoms of low testosterone—but it rarely travels alone. When other hormones are also out of balance, that fatigue deepens. And when it’s paired with other symptoms, the spiral can feel even steeper.
The Depression–Fatigue Loop
Fatigue is often entangled with depression. For some men, hormone-related depression fuels exhaustion. For others, it’s the other way around—persistent fatigue feeds low mood. Sleep struggles often enter the mix, compounding the problem. It’s a feedback loop that quietly chips away at your quality of life.
Sweating Through the Night
Hormonal imbalances can also lead to hot flashes, and when they strike during sleep, you’re left tossing, turning, and waking up unrefreshed. Over time, disrupted sleep leads to full-body fatigue throughout the day.
Metabolic Sluggishness
Your body’s ability to convert food into fuel slows down when hormone levels shift. That metabolic dip means lower energy, even if you’re eating well and staying active.
Stress, Cortisol & Burnout
Ongoing fatigue can put your body under constant stress. In response, your adrenal glands pump out cortisol. But if stress sticks around too long, those glands can burn out—leading to inconsistent cortisol levels, poor resilience, and deeper fatigue.
How We Treat It
The solution begins with restoring hormonal balance. Once testosterone and other key hormones are optimized, your body regains its rhythm. Sleep deepens, depression eases, metabolism picks back up, and energy returns. It’s not just about treating fatigue—it’s about getting your edge back.
Low Sex Drive
Low Sex Drive in Men
A reduced interest in sex is a common effect of hormonal imbalance. Of course, “low” looks different for every man — but if your sex drive feels noticeably lower than what’s normal for you, it’s worth paying attention to.
Key Hormones That Influence Libido
Testosterone: The Driving Force
Testosterone is the primary hormone behind male sexual desire. Think of it as fuel — without enough in the tank, libido naturally declines.
Estrogen: Too High or Too Low
Yes, men produce estrogen too — in small, beneficial amounts. It plays a role in brain, bone, and heart health. But when levels rise too high, it can interfere with sex drive. Surprisingly, too little estrogen may also have a negative impact. Either scenario can show up during andropause.
When Both Are Out of Sync
Some men experience a combination of low testosterone and imbalanced estrogen. This dual disruption can significantly reduce sexual interest — sometimes to zero.
Prolactin’s Role
Less commonly discussed, prolactin is another hormone that can play a role. Elevated levels — which typically relate to nurturing behavior — may reduce sex drive in men and interfere with sexual satisfaction.
How We Treat It
Our approach focuses on restoring healthy hormone balance — especially testosterone — while carefully monitoring estrogen. If prolactin levels are elevated, we’ll address that too. With targeted therapy and your engagement, your energy, confidence, and desire can return. It’s possible to feel like yourself again — or even better.
Weight Gain
Weight Gain in Men
Trying to lose weight with imbalanced hormones can feel like pushing a boulder uphill. The more out of sync your system is, the steeper the climb becomes.
Why Hormones Matter
Hormones regulate your metabolism, which determines how effectively your body burns calories and stores fat.They also impact your ability to maintain muscle mass—and since muscle burns more calories than fat, less muscle usually means a slower metabolism.Hormones affect motivation and activity levels, making it harder to stay energized and consistent with healthy habits.
How We Help Address Weight Gain
Our treatment strategy includes a combination of hormone optimization, lifestyle shifts, and metabolic support:
We restore balance to key hormones like testosterone, estrogen, and thyroid, giving your body the signal it needs to burn fat efficiently.We help reduce insulin overload by encouraging lower intake of refined carbohydrates—excess insulin tells the body to store fat.We promote regular physical activity tailored to your needs. With hormones back in sync, energy returns and workouts become sustainable.We address stress, which can elevate cortisol and encourage fat storage—especially around the midsection.We offer additional support, such as injectable nutrient therapies, when appropriate.
The Long Game
It all starts with fixing the hormonal foundation. From there, we help you tackle the pieces one at a time—until they stick. If you stumble (everyone does), it’s your ability to keep going that creates real, lasting results.
Muscle Loss
Muscle Loss in Men
Noticing a loss in strength or definition? Struggling to build or maintain muscle like you used to? These can be signs that your testosterone levels are running low.
What Contributes to Muscle Loss:
Testosterone
This hormone is essential for protein synthesis — the process your body uses to build muscle. When testosterone drops, it becomes harder to maintain or increase lean mass, even with proper exercise and nutrition.
Lack of Physical Activity
Even optimal hormone levels won’t help if your muscles aren’t being used. Resistance training is what activates muscle growth — testosterone supports the process, but activity drives it.
Nutritional Gaps
Your body needs protein, amino acids, and other key nutrients to recover and rebuild muscle. A diet high in sugar and low in quality protein or micronutrients can stall your progress, no matter how hard you train.
Our Treatment Approach
We start by optimizing testosterone levels through safe, effective therapy. But we don’t stop there.
We recommend resistance-based exercise routines to activate muscle growth.We support your body with nutrition guidance and, when needed, injectable nutrient therapies. In some cases, peptides or growth hormone therapies can also help maximize muscle development and recovery.
With the right combination of hormones, movement, and fuel, rebuilding strength isn’t just possible — it’s expected.
Insomnia
Insomnia in Men
When hormones fall out of balance, restful sleep is often one of the first casualties. Insomnia, restless nights, and early wakeups become the new normal — but they don’t have to.
What Drives Hormone-Related Sleep Problems
Low Serotonin
Serotonin plays a major role in regulating sleep cycles — and testosterone plays a role in serotonin production. When testosterone is low, serotonin often follows, making it harder to fall asleep and stay asleep.
Mood & Mental Health
Anxiety and depression frequently interfere with sleep. And when testosterone, thyroid, or estrogen levels are off, mood imbalances can develop, creating a ripple effect on your ability to rest.
Sleep Apnea
There’s a strong link between low testosterone and obstructive sleep apnea. If you’re experiencing breathing interruptions during sleep, deeper rest becomes nearly impossible.
Night Sweats
Hormonal shifts — especially low testosterone — can lead to nighttime temperature surges. Waking up drenched or uncomfortable can ruin quality sleep night after night.
Growth Hormone Disruption
Your body produces growth hormone primarily during deep sleep. Poor sleep reduces GH production — and lower GH can further disrupt sleep, energy, and recovery.
Adrenal Imbalance
Cortisol, your stress hormone, should follow a predictable daily rhythm. When the adrenal system is dysregulated, cortisol surges (or drops) at the wrong times — and sleep suffers.
How We Treat It
We understand that sleep and hormone balance are deeply connected. Our physicians work to restore testosterone, estrogen, thyroid, and adrenal hormones to optimal levels. Where helpful, we also offer support like peptide therapies or lifestyle strategies that encourage deeper, uninterrupted rest.
Better sleep isn’t just possible — it’s part of the plan.
When your body is balanced, your nights become restorative again. And that makes everything else better, too.
Mood Changes
Mood Changes in Men
When testosterone levels are healthy, the male brain carries a high concentration of this vital hormone — and that matters. Testosterone plays a direct role in regulating serotonin, a key neurotransmitter for emotional balance. So when testosterone drops, serotonin usually does too… leading to irritability, low motivation, and mild to moderate depression.
What’s Behind the Mood Shift?
Low testosterone is a common underlying cause of ongoing irritability and low mood in men.Other hormones like estrogen, thyroid, DHEA, and cortisol can amplify mood symptoms when out of balance.Depression in men often flies under the radar — sometimes showing up not as sadness, but as burnout, apathy, or short temper.
The Problem with Temporary Fixes
It’s common for men to be prescribed antidepressants when they mention emotional symptoms to their doctor. But these medications often bring unwanted side effects: lower libido, worsened sexual function, and even more mood instability.
More importantly, they may not solve the actual problem.
In many men, depression and emotional flatness are symptoms of hormone imbalance, not standalone disorders. In those cases, medication is a band-aid — not a solution.
How We Treat It
We take a root-cause approach. By restoring testosterone and other hormones to optimal levels, we help rebalance brain chemistry, naturally improving mood and motivation.
Many of our clients say the same thing:
“I just wanted to feel like myself again."
With a personalized treatment plan, that’s exactly what we help you achieve — more clarity, more stability, and more joy in daily life.
Brain Fog
Brain Fog in Men
Struggling to concentrate? Forgetting names or losing your train of thought more often? If your mental clarity isn’t what it used to be, hormonal imbalance may be at the root of it.
What Causes Brain Fog?
Hormonal Disruptions
Testosterone, thyroid hormones, and even estrogen all play important roles in supporting memory, mental clarity, and focus. When any of these are off, your brain’s neurotransmitters may not function at their best — making it harder to process, retain, or recall information.
Stress & Cortisol Overload
High stress levels elevate cortisol, your body’s main stress hormone. While cortisol is essential in small amounts, prolonged elevation can negatively impact brain function — especially memory and decision-making.
Should You Be Concerned?
Mild forgetfulness or mental fuzziness that starts during andropause is often reversible. But if ignored, these early symptoms can progress. Research increasingly shows that unbalanced hormone levels may contribute to long-term cognitive decline in aging men.
Our Approach to Treating Brain Fog
Brain fog doesn’t have to become your new normal. We address it by restoring hormonal balance, improving neurotransmitter function, and supporting brain health from multiple angles. In addition to testosterone and thyroid optimization, we may recommend targeted therapies like:
Injectable nutrients to support brain and cellular functionPhysician-guided nootropics for sharper focus and mental stamina
With the right treatment plan, mental clarity and confidence can return — so you can perform at your best again.
Erectile Dysfunction
Understanding Erectile Dysfunction in Men
Erectile dysfunction (E.D.) can have a variety of root causes — but just as importantly, it has solutions. If you take away one thing from this section, it’s this:
we can help.
How Common Is E.D.?
You’re not alone. E.D. is more common than many men realize:
By age 40, about 40% of men experience some degree of E.D. By age 70, that number climbs to 70%.Across all adult ages, over 50% of men deal with E.D. at some point. In the U.S. alone, more than 30 million men are affected.
What Causes Erectile Dysfunction?
Low Testosterone
Testosterone is essential for male sexual function — and it needs to be at a strong, healthy level to support desire and performance.
Elevated Estrogen
Men need some estrogen for things like brain, bone, and cardiovascular health. But too much estrogen — especially when testosterone is low — can significantly interfere with sexual performance.
Medical Conditions & Medications
Several health issues and medications are known contributors to E.D., including:
DiabetesHigh blood pressureHeart diseaseProstate conditionsCertain surgeriesAntidepressants, blood pressure meds, and blood thinners
Our Treatment Approach
There are more effective options for treating E.D. today than ever before — the key is finding the right combination for you.
We begin by optimizing your hormones, especially testosterone and estrogen. If E.D. symptoms persist after your hormones are in balance, we’ll guide you through additional evidence-based treatments tailored to your needs.
Because every man deserves a fulfilling, satisfying sex life — and with the right support, it’s absolutely within reach.
Hair Loss
Hair Loss in Men
We take a thoughtful, experience-driven approach to treating hair loss — guided by 25+ years of results, clinical insight, and common sense.
What Causes Hair Loss in Men?
DHT Sensitivity
Some testosterone naturally converts into DHT (dihydrotestosterone), a hormone that supports sex drive but can also trigger hair loss — particularly in men with genetically DHT-sensitive hair follicles. This is usually hereditary and shows up in men who begin losing hair in their 20s or early 30s.
Low Thyroid Function
A decline in thyroid hormones is another common cause of hair loss, especially in aging adults. In fact, we often find thyroid-related hair thinning is more prevalent than DHT-driven loss. The good news: when thyroid levels are restored to optimal ranges, hair loss typically stops — and in many cases, regrowth follows.
Stress & Cortisol Imbalance
Chronic stress disrupts many of the body’s natural rhythms, and hair health is no exception. Excess or deficient cortisol can interfere with hair growth cycles. Managing stress and supporting adrenal function are critical to improving hair health from the inside out.
Our Treatment Approach
Hair loss doesn’t have to be inevitable — and we’re here to support you with options that target the real root causes. Here’s how we typically approach treatment:
Optimize thyroid levels when deficiencies are presentSupport healthy testosterone levels, which benefit hair when properly balancedAddress excess DHT in men with DHT-sensitive follicles using topical or oral treatmentsManage stress and regulate cortisol, whether it’s too high or too low
It’s also important to know: testosterone therapy doesn’t automatically mean hair loss.
We’ll walk you through your options, answer your questions, and build a plan that works for your body and your goals — including your hair.
Where Wellness Meets Science.
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